| ncRNA name | Pax6 siRNA |
| ncRNA Category | siRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell lines Y79, WERI-RB1 and SO-RB50 |
| Methods | siRNA transfection, qPCR, Western blot, CCK-8 assay, flow cytometry, TUNEL assay, immunofluorescence |
| Expression pattern | associated |
| Functional description | Silencing the Pax6 gene with short interfering RNA resulted in an inhibited growth and an increased apoptosis of cultured human retinoblastoma cells. It was paralleled by upregulation of the P21 and P27 proteins. |
| PubMed ID | 21169528 |
| Year | 2011 |
| Title | Pax6 regulates proliferation and apoptosis of human retinoblastoma cells. |
| Drug-related ncRNA | NO |
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